# GATOR1

Scientists Map a 'Molecular Brake' That Tunes Cell Growth — New Target for Cancer and Neurological Disease

Monash University researchers used cryo‑EM to determine the near‑atomic structure of the KICSTOR–GATOR1 complex, revealing how it suppresses cell growth in low‑nutrient conditions. The finding clarifies a major node in the mTOR nutrient‑sensing pathway and suggests new, potentially more selective therapeutic avenues for cancers and certain neurological disorders linked to growth‑control failure.